Publicación: Fisiopatología de la sepsis por gram positivos
| dc.contributor.author | Méndez Fandiño, Yardany Rafael | spa |
| dc.contributor.author | Barrera C., María Claudia | spa |
| dc.date.accessioned | 2017-07-07T10:13:15Z | |
| dc.date.accessioned | 2025-08-05T14:24:52Z | |
| dc.date.available | 2017-07-07T10:13:15Z | |
| dc.date.available | 2025-08-05T14:24:52Z | |
| dc.date.issued | 2017-07-07 | |
| dc.description.abstract | Las bacterias gram positivas vienen cobrando importancia como agentes etiológicos de la sepsis siendo algunos de principales representantes Staphylococcus aureus, las cepas de S.aureus meticilino resistentes (MRSA del inglés) y el Streptococcus pyogenes o también llamado Streptococcus del grupo A invasivo (GAS). Dado que en su estructura celular presentan diversas moléculas que pueden ser reconocidas como patrones moleculares asociados a patógenos (PAMPs) como son el peptidoglicano (PNG) el ácido teicoico (LTA), las lipoproteínas; y otras que activan directamente el sistema inmune adaptativo como son los Superantígenos; los pacientes infectados pueden exponerse de manera simultánea a una respuesta inmune amplifi cada de manera sinérgica entre todos estos tipos de antígenos, que a través de vías de señalización intracelular desencadenarán la transcripción de genes codifi cadores de citocinas pro infl amatorias como el TNFα, la IL-1β, la IL-6, el INFγ, IL-8, IL-18, IL-2, IL-12, IL-10 que darán lugar a muchas de las manifestaciones clínicas de la sepsis y se vienen asociando como predictores del pronóstico de esta junto a otros marcadores moleculares de la misma. | spa |
| dc.description.abstract | Gram positive bacteria are becoming important as etiological agents of sepsis, with some of the main representatives of Staphylococcus aureus, strains of S. aureus methicillin resistant (MRSA) and the Streptococcus pyogenes or also Streptococcus group A invasive (GAS). Since in their cellular structure they present several molecules that can be recognized as molecular pathogen associated pathogens (PAMPs) such as peptidoglycan (PNG), teicoico acid (LTA), lipoproteins; and others that directly activate the adaptive immune system such as Superantigens; infected patients can be exposed simultaneously to a synergistically amplifi ed immune response among all these types of antigens, which through intracellular signaling pathways will trigger the transcription of genes encoding pro-infl ammatory cytokines such as TNFα, IL-1β, IL-8, IL-12, IL-12, IL-10, IL-10, which will lead to many of the clinical manifestations of sepsis and are associated as predictors of prognosis of this with other molecular markers of the same | eng |
| dc.format.mimetype | application/pdf | spa |
| dc.identifier.doi | 10.26752/cuarzo.v22.n1.146 | |
| dc.identifier.eissn | 2500-7181 | |
| dc.identifier.issn | 0121-2133 | |
| dc.identifier.uri | https://repositorio.juanncorpas.edu.co/handle/001/381 | |
| dc.identifier.url | https://doi.org/10.26752/cuarzo.v22.n1.146 | |
| dc.language.iso | spa | spa |
| dc.publisher | Fundación Universitaria Juan N. Corpas | spa |
| dc.relation.bitstream | https://revistas.juanncorpas.edu.co/index.php/cuarzo/article/download/146/141 | |
| dc.relation.citationendpage | 65 | |
| dc.relation.citationissue | 1 | spa |
| dc.relation.citationstartpage | 51 | |
| dc.relation.citationvolume | 22 | spa |
| dc.relation.ispartofjournal | Revista Cuarzo | spa |
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| dc.rights | Yardany Rafael Méndez Fandiño, María Claudia Barrera C. - 2017 | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/4.0/ | spa |
| dc.source | https://revistas.juanncorpas.edu.co/index.php/cuarzo/article/view/146 | spa |
| dc.subject | Sepsis | eng |
| dc.subject | Gram-Positive Bacteria | eng |
| dc.subject | Molecular | eng |
| dc.subject | Virulence Factors | eng |
| dc.subject | Clinical Pathology. | eng |
| dc.subject | Sepsis | spa |
| dc.subject | Bacterias Gram positivas | spa |
| dc.subject | Molecular | spa |
| dc.subject | Factores de virulencia | spa |
| dc.subject | Patología clínica. | spa |
| dc.title | Fisiopatología de la sepsis por gram positivos | spa |
| dc.title.translated | Towards an educational proposal to promote undergraduates’ professional identity | eng |
| dc.type | Artículo de revista | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_dcae04bc | spa |
| dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
| dc.type.content | Text | spa |
| dc.type.driver | info:eu-repo/semantics/article | spa |
| dc.type.local | Journal article | eng |
| dc.type.redcol | http://purl.org/redcol/resource_type/ARTREV | spa |
| dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
| dspace.entity.type | Publication | spa |